Prematurity

Prematurity

Preterm birth is defined as any birth before 37 completed weeks of gestation (37+0). It has been estimated to account for up to 11 % of all births. Preterm birth is a substantial cause of neonatal and pediatric morbidity and mortality. Prematurity is the single most important cause of death in the…

Polycythemia

Polycythemia

Polycythemia is defined by venous hemoglobin concentration > 220 g/l or by hematocrit value > 0.65 during the first week of life. It correlates clinically with hyperviscosity syndrome. The common causes: chronic intrauterine hypoxia twin-twin transfusion syndrome in monochorionic-diamniotic twins (recipient twin) excessive placental transfusion Diagnosis Clinical signs dictated by the severity of hyperviscosity syndrome (infant…

Necrotizing enterocolitis

Necrotizing enterocolitis

Necrotizing enterocolitis (NEC) belongs to acute abdomen events (inflammatory subgroup). It is typical disease of extreme prematurity – incidence is inversely proportional to advancing gestational age (1-5% of newborns admitted to the neonatal intensive care unit). Mortality associated with NEC varies between 20-50%. Multifactorial basis of NEC makes it difficult to pinpoint single…

Acute abdomen

Acute abdomen

Acute abdomen events arise from a number of diseases based on the predominant pathophysiology. They require urgent revision. Basic division of acute abdomen in newborns: congenital gastrointestinal malformations non-inflammatory→ ileus of prematurity (IOP)→ spontaneous intestinal perforation (SIP)→ incarceration of inguinal hernia→ testicular torsion (unilateral orchidectomy) inflammatory→ necrotizing enterocolitis (NEC)→ peritonitis (usually…