Trombophilia
Inherited thrombophilia permanent condition that can increase the risk for thrombosis formation in presence of other factors or triggers (see acquired conditions below) Leiden mutation of factor 5 = the …
Hematology
Bleeding disorders
Newborns (preterm in particular) have relatively low levels of pro-coagulation factors (vitamin K dependent factors), diminished platelet functions (their levels are similar to adults), as well as low anti-coagulation factors …
Leucocyte abnormalities
There are significant differences in white blood cell (WBC) total and differential counts between newborns and older children. Alterations in WBC total and differential count can be an early sign …
Polycythemia
Polycythemia is defined by venous hemoglobin concentration > 220 g/l or by hematocrit value > 0.65 during the first week of life. It correlates clinically with hyperviscosity syndrome. The common …
Anemia
Hemoglobin production begins around the third week of pregnancy in the cytoplasm of embryonic red blood cells in the yolk sac. Hematopoietic stem cells then colonize other organs and hematopoiesis …
Hyperbilirubinemia
Hyperbilirubinemia is defined as serum bilirubin concentration > 25 μmol/l. However, clinical presentation (jaundice (icterus) – yellowish colouring of the skin, sclera and mucosa) is apparent in newborns usually around …