Pulmonary hypertension
Persistent pulmonary hypertension of newborns (PPHN) is characterized by postnatally persistent vasoconstriction of the pulmonary arteries, causing increased pulmonary arterial resistance. As a consequence, right-left shunting (extra-pulmonary shunts) occurs through foramen ovale apertum (FOA) and patent ductus arteriosus (PDA) with resultant hypoxemia. Also, pulmonary arteries in neonates are more prone to vasoconstriction than in adults. There is primary (impaired development…