Congenital heart defects

Congenital heart defects

Critical congenital heart defects (CCHD) present during the neonatal period with cyanosis and/or cardiac failure depending on the particular defect and its severity. The incidence of the CCHD is approximately 1-3 : 1000. These defects can be diagnosed antenatally, however, anomaly scan detection rates vary significantly among different countries and also within the same country (e.g. 33-70% prenatal CCHD diagnosis in…

Necrotizing enterocolitis

Necrotizing enterocolitis

Necrotizing enterocolitis (NEC) belongs to acute abdomen events (inflammatory subgroup). It is typical disease of extreme prematurity – incidence is inversely proportional to advancing gestational age (1-5% of newborns admitted to the neonatal intensive care unit). Mortality associated with NEC varies between 20-50%. Multifactorial basis of NEC makes it difficult to pinpoint single…