Neonatal thrombophilia can cause both arterial and venous thromboembolic events. Thrombophilia results from the disrupted hemostatic system that normally consists of 4 integrated components: the coagulation system, endothelium and regulatory proteins, platelets, and fibrinolysis. The peak incidence of pediatric thromboembolic events occurs in neonates and infants < 1 year of age….
Early onset sepsis (EOS) is an infectious complication in newborns that have clinical presentation within the first 72 hours of life. Sometimes also called perinatal due to pathogenesis – vertical transmission shortly before the birth (transplacental), ascendent infection from the cervicovaginal space (chorioamnionitis, funisitis, fetal infection) or during the vaginal delivery. The pathogen can be also the cause…
Late onset sepsis (LOS) is an infectious complication in newborns that have clinical presentation after the first 72 hours of life. Sometimes also called nosocomial due to pathogenesis – contact with mother, breastmilk, invasive procedures, hands of healthcare personnel. LOS episodes significantly contribute to neonatal mortality and morbidity rates and can have lifelong…
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