Neurodevelopment

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The central nervous system of extremely preterm infants is highly susceptible to perinatal injuries due to the presence of immature vasculature in the germinal matrix and periventricular white matter. Furthermore, …

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Periventricular leukomalacia

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The central nervous system of extremely preterm infants is highly susceptible to perinatal injuries due to the presence of immature vasculature in the germinal matrix and periventricular white matter. Furthermore, …

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Intraventricular hemorrhage

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The hemorrhage in the preterm infants usually originates in the germinal matrix (temporary developmental structure with significant vascular supply due to massive mitotic and metabolic activity). The structure is divided …

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Congenital disorders of nervous system

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Congenital anomalies of nervous system can be detected by the prenatal screening (ultrasound – hydrocephalus, anencephalus; biochemistry using alpha-fetoprotein (AFP) – elevated in amniotic fluid and maternal serum in neural …

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Seizures

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There is a number of different types of seizure activity in newborns. Seizure types subtle seizures (grimace, blinking, yawning, salivation, cycling, apnea) myoclonus clonic seizures (unifocal, multifocal) tonic seizures (generalized …

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Microcephaly & Macrocephaly

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Primary prerequisite for the diagnosis of microcephaly/macrocephaly is the proper horizontal head circumference (HC) measurement (frontal-occipital circumference): supine position glabella – opisthocranion as anchor points normocephaly (32-38 cm for a …

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